Digital potentiometer

I want to control a digital potentiometer with wled, maybe even 2 to control non pwm dimmers for white led strips that wont have any flicker

If you have some example parts in mind and/or some example conceptual drawings, we might be able to give some suggestions.
At first blush, I would expect this to be a usermod.

Havent settled on a part but i did notice for led strip options theres pwm, trying to find a board to take pwm from esp8266 and output either higher frequency pwm, variable current, or variable voltage. Might need a user mod for some other communication standards

I’m looking to replace a potentiometer on a DC-to-DC constant current booster with a digital potentiometer, like the MCP41HV51-104E/ST, to control and dim a high-power COB LED. Is it possible to control this setup with WLED?

no. you’ll need to develop a usermod